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Thessaloniki (Greek: Θεσσαλονίκη [θesaloˈnici]), also known as  Thessalonica ( /ˌθɛsəlɵˈnaɪkə/ or /ˌθɛsəˈlɵnɪkə/) and Salonica, is the second-largest city in Greece and the capital of the region of Central Macedoniaas well as the capital of the Decentralized Administration of Macedonia and Thrace. Its honorific title is Συμπρωτεύουσα (Symprotévusa), literally "co-capital", and stands as a reference to its historical status as the Συμβασιλεύουσα (Symvasilévousa), "co-reigning" city of the Byzantine Empire, alongside Constantinople.