Aetolia-Acarnania (Greek: Αιτωλοακαρνανία, Aitoloakarnanía) is one of the regional units of Greece. It is part of the region of West Greece. It is located in the western part of Greece; the regional unit is a combination of the geographic regions Aetolia andAcarnania. Its capital is Missolonghi for historical reasons, with its biggest city and economic centre at Agrinio. The area is now connected with the Peloponnese peninsula via the Rio-Antirio Bridge. The surrounding regional units take in Arta in Epirus, a narrow length bordering Karditsa of Thessaly, Evrytania to the northeast, and Phocis to the east. This is the largest regional unit in Greece.